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Cat. No. Product Name Target Signaling Pathways
T16568 PR-924

Proteasome Proteases/Proteasome; Ubiquitination
PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 inhibits growth and triggers apoptosis in multiple myeloma (MM) cells. PR-924 has antitumor activities. PR-924 covalently modifies proteasomal N-terminal threonine active sites.

化合物

PR-924
Cat.No: T16568
Synonym:
Target: Proteasome
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