Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38715 |
MSDC-0602K
MSDC-0602K,Azemiglitazone potassium |
PPAR | DNA Damage/DNA Repair; Metabolism |
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). This compound, MSDC-0602K, has potential applications in researching fatty liver conditions, including dysfunctional lipid metabolism, inflammation, and insulin resistance. MSDC-0602K acts as an insulin sensitizer, improving insulinemia and fatty liver disease in mice both ... |