Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17095 |
TIK-301
PD-6735,LY-156735 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM, respectively). TIK-301 is also a 5-HT2B/5-HT2C receptor antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment. |