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Cat. No. Product Name Target Signaling Pathways
T36455 11β-Prostaglandin F2α

11β-Prostaglandin F2α

11β-Prostaglandin F2α 是一种由 AKR1C3 催化的生物活性代谢物,可刺激前列腺素 F 受体并诱导乳腺癌中的 slug 表达。11β-Prostaglandin F2α 也是存在于尿液中的内源代谢物。
T37275 2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α

2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2,3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2,3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α wh...
T38114 AL 8810 ethyl amide

AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modified to an N-ethyl amide. This modification is analogous to the PG N-ethyl amides, as typified by Bimatoprost, that have been introduced as alternative PG ocular hypotensive prodrugs. In contrast to AL 8810 which contracted the cat iris, AL 8810 ethyl amide showed no contraction ac...

化合物

11β-Prostaglandin F2α
Cat.No: T36455
Synonym: 11β-Prostaglandin F2α
Target:
2,3-dinor-11β-Prostaglandin F2α
Cat.No: T37275
Synonym: 2,3-dinor-11β-Prostaglandin F2α
Target:
AL 8810 ethyl amide
Cat.No: T38114
Synonym:
Target:
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