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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T37547 trans-Urocanic Acid

trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic ...
T10824 cis-Urocanic acid

cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸

5-HT Receptor GPCR/G Protein; Neuroscience
cis-Urocanic acid ((E)-Urocanic acid) 是一种 5-HT2A 受体激动剂,cis-Urocanic acid 与 5-HT 受体结合的Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂,通过与 5-HT2A 受体结合而诱导免疫抑制。

化合物

trans-Urocanic Acid
Cat.No: T37547
Synonym:
Target:
cis-Urocanic acid
Cat.No: T10824
Synonym: cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸
Target: 5-HT Receptor
Cat. No. Product Name Target Signaling Pathways
T4759 Urocanic acid

4-Imidazoleacrylic acid,尿刊酸

Others; Endogenous Metabolite Metabolism; Others
Urocanic acid(4-Imidazoleacrylic acid)存在于表皮中,是哺乳动物皮肤中紫外线(UV)辐射的主要吸收物。

天然产物

Urocanic acid
Cat.No: T4759
Synonym: 4-Imidazoleacrylic acid,尿刊酸
Target: Others, Endogenous Metabolite
TargetMol Loading
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