Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1527 |
Gliclazide
格列齐特,S1702,SE1702 |
Potassium Channel | Membrane transporter/Ion channel |
Gliclazide (SE1702) 是一种有效的全细胞的 β 细胞 ATP 敏感型钾流阻断剂,IC50为 184 nM,用作降糖药。 | |||
T71981 |
Gliclazide-d4
|
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Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin... |