Cat. No. | Product Name | Target | Signaling Pathways |
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T80515 |
β-Endorphin (1-27) (human)
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Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
β-Endorphin (1-27) (human) 是一种 opioid 拮抗剂,与 μ-、δ- 及 κ-阿片受体结合,其 Kis 分别为 5.31、6.17 及 39.82 nM。该化合物还能够抑制由 β-Endorphin 及 etorphine 引起的痛觉消失。 | |||
T38193L |
β-Endorphin (1-27) (human) acetate
β-Endorphin (1-27) (human) acetate(76622-84-9 Free base) |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
β-Endorphin (1-27) (human) acetate 存在于大脑垂体和下丘脑中,具有镇痛活性。 β-Endorphin (1-27) (human) acetate 是一种阿片受体激动剂,对 μ-阿片受体和 δ-阿片受体具有较好的亲和力。 | |||
T38193 |
β-Endorphin (1-27) (human) (trifluoroacetate salt)
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β-Endorphin (1-27) is an endogenous peptide that binds to μ-, δ-, and κ-opioid receptors (Kis = 5.31, 6.17, and 39.82 nM, respectively, in COS-1 cells expressing rat receptors). It binds to rat and mouse brain membrane preparations (IC50s = 1.1 and 5.7 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 1 nM. Intracerebroventricular administration of β-endorphin (1-27) increases the latency to tail withdrawal in response to thermal stimulation in ... |