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Cat. No. Product Name Target Signaling Pathways
T10526 β-NF-JQ1

Others Others
β-NF-JQ1是一种PROTAC,可将芳烃受体E3 (AhR E3) 连接酶招募到目标蛋白上。β-NF-JQ1使用β-NF 作为AhR 配体靶向含溴odomain(BRD)的蛋白,诱导AhR 和BRD 蛋白相互作用。β-NF-JQ1显示出与蛋白敲除活性相关的强大的抗癌活性 。
T13981 β-Naphthoflavone-CH2-Br

β-NF-CH2-Br

Others Others
β-Naphthoflavone-CH2-Br is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br used to synthesize the PROTAC β-NF-JQ1.
T16312 NH2-PEG3

PROTAC Linker 35

Others Others
NH2-PEG3 (PROTAC Linker 35) is a polyethylene glycol (PEG) linker utilized in the synthesis of PROTAC (β-NF-JQ1)[1].
T17363 β-Naphthoflavone-CH2-OH

β-NF-CH2-OH

Others Others
β-Naphthoflavone-CH2-OH (β-NF-CH2-OH) serves as an AhR E3 ligase ligand, forming chimeric molecules when connected to a protein ligand through a linker, resulting in PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1). These chimeric molecules recruit the AhR E3 ligase complex by incorporating AhR ligands. By inducing ubiquitination-mediated degradation, PROTACs effectively target and degrade cancer-promoting proteins [1].

化合物

β-NF-JQ1
Cat.No: T10526
Synonym:
Target: Others
β-Naphthoflavone-CH2-Br
Cat.No: T13981
Synonym: β-NF-CH2-Br
Target: Others
NH2-PEG3
Cat.No: T16312
Synonym: PROTAC Linker 35
Target: Others
β-Naphthoflavone-CH2-OH
Cat.No: T17363
Synonym: β-NF-CH2-OH
Target: Others
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