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Cat. No. | Product Name | Target | Signaling Pathways |
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TP2044 |
α-CGRP(human)
α-CGRP (human) |
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Endogenous calcitonin gene-related peptide receptor (CGRP) agonist. | |||
TP2044L |
α-CGRP (human) acetate
人类降钙素基因相关肽 1,α-CGRP (human) acetate (90954-53-3 free base) |
Others | Others |
α-CGRP (human) acetate 是一种由 37 个氨基酸组成的调节性神经肽。它是一种有效的血管扩张剂,具有正性肌力作用和变时性作用。 | |||
T36555 |
Tyr-α-CGRP (human) (trifluoroacetate salt)
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Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively). Tyr-α-CGRP also binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM). It also binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively), induces positive chronotropic and inotropic effects in isolated rig... | |||
TP1134 |
HCGRP-(8-37)
Human α-CGRP (8-37) |
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Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist | |||
T75788 |
α-CGRP(human) TFA
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α-CGRP(human) TFA,一种含37个氨基酸的调节性神经肽,广泛存在于中枢神经系统和周围神经系统中,是一种高效的血管扩张剂。 | |||
T75978 |
β-CGRP, human TFA
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β-CGRP, human TFA (Human β-CGRP TFA) 是一种降钙素肽,通过降钙素受体样受体CRLR 与RAMP 的复合物起作用,在细胞体系中,对 CRLR/RAMP1 和 CRLR/RAMP2 的IC50值分别为 1 nM 和 300 nM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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TP2167 |
β-CGRP, human acetate
β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate |
CGRP Receptor | GPCR/G Protein; Neuroscience |
β-CGRP, human acetate 是降钙素肽之一,通过受体活性修饰蛋白 (RAMP) 和降钙素受体样受体 (CRLR) 的复合物发挥作用(对于 CRLR/RAMP1 和 CRLR,IC50:1 nM 和 300 nM /RAMP2 在单元格中)。 |