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Cat. No. Product Name Target Signaling Pathways
T18662 (S,R,S)-AHPC-C2-PEG4-N3

VH032-C2-PEG4-N3

Others Others
(S,R,S)-AHPC-C2-PEG4-N3 (VH032-C2-PEG4-N3) is a synthesized E3 ligase ligand-linker conjugate combining the (S,R,S)-AHPC-based VHL ligand with a 4-unit polyethylene glycol (PEG) linker, employed in PROteolysis TAgeting Chimera (PROTAC) technology. This compound facilitates the creation of vRucaparib-TP4, a potent PARP1 degrader demonstrating a half-maximal degrading concentration (DC50) of 82 nM[1].

化合物

(S,R,S)-AHPC-C2-PEG4-N3
Cat.No: T18662
Synonym: VH032-C2-PEG4-N3
Target: Others
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