Cat. No. | Product Name | Target | Signaling Pathways |
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T20482 |
Acth (1-4)
(1-4) Corticotropin |
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Acth (1-4) is the ACTH N-terminal tetrapeptide. | |||
T7361 |
Verucerfont
NBI77860,3-(4-甲氧基-2-甲基苯基)-2,5-二甲基-N-[(1S)-1-(3-甲基-1,2,4-恶二唑-5-基)丙基]吡唑并[1,5-A]嘧啶-7-胺,GSK561679 |
CRFR | GPCR/G Protein |
Verucerfont (NBI77860) 是促肾上腺皮质激素释放因子受体 1 (CRF1) 拮抗剂,作用于 CRF1(IC50:6.1 nM),CRF2 (IC50>1000 nM)和 CRF-BP (IC50>1000 nM)。 | |||
T35814 |
Urocortin III (human) (trifluoroacetate salt)
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Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively).... |