Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13461 |
(+)-Cloprostenol
D-Cloprostenol |
Others | Others |
(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic. | |||
T5847 |
Cloprostenol sodium salt
ICI 80996 sodium salt,DL-Cloprostenol sodium,氯前列烯醇钠,氯前列烯醇纳,Cloprostenol sodium |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Cloprostenol sodium salt (ICI 80996 sodium salt) 是一种合成的前列腺素类似物,是 PGF2α受体的激动剂,具有黄体溶解性。 | |||
T37231 |
(+)-Cloprostenol methyl ester
|
Others | Others |
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprosteno... | |||
T37230 |
(+)-5-trans Cloprostenol
|
Others | Others |
Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster. | |||
T29245 |
(+)-Cloprostenol sodium
D-Cloprostenol,D-Cloprostenol sodium salt |
Others | Others |
(+) - cloprostenol sodium is a kind of water-soluble prostaglandin F2 α ( PGF2 α) Analogues. It is an FP receptor agonist and a potent luteinizing agent in rats and hamsters. | |||
T20592 |
Cloprostenol
Estrofan,Oestrophan |
Others | Others |
Cloprostenol is a synthetic analogue of prostaglandin. | |||
T29246 |
Cloprostenol isopropyl ester
(+)-16-m-chlorophenoxy tetranor Prostaglandin F2α isopropyl ester,(+)-Cloprostenol isopropyl ester |
Others | Others |
Cloprostenol isopropyl ester is a PGF2α agonist and a similar synthetic prostaglandin F2α (PGF2α), which can induce luteal dissolution in mares during the luteal phase without causing clinical side effects or stress responses. | |||
T2538 |
Bimatoprost
AGN 192024,比马前列素 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Bimatoprost (AGN 192024) 是一种氯前列醇衍生的酰胺,用作治疗开角型青光眼和高眼压症的抗高血压药。 | |||
T37946 |
17-trifluoromethylphenyl trinor Prostaglandin F2α
17-trifluoromethylphenyl trinor Prostaglandin F2α |
Others | Others |
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trin... |