4
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4550L |
Ajmaline hydrochloride
|
||
Ajmaline hydrochloride is an alkaloid found in the root of Rauwolfia serpentina, and other plant sources. It is a class of Ia antiarrhythmic agent that apparently works by changing the shape and threshold of cardiac action potentials. | |||
T25979L |
Prajmalium bitartrate
Neo-gilurytmal,NPAP |
||
Prajmalium bitartrate, a derivative of the rauwolfia alkaloid AJMALINE, is an anti-arrhythmia agent but may cause liver damage. | |||
T25755 |
Lorajmine
Lorajmina |
||
Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases. | |||
T25979 |
Prajmalium
Prajmalum |
||
Prajmalium, a derivative of the rauwolfia alkaloid AJMALINE, is an anti-arrhythmia agent but may cause liver damage. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4550 |
Ajmaline
Cardiorythmine,Raugalline,阿义吗啉,阿义马林,Tachmalin,(+)-Ajmaline |
Sodium Channel | Membrane transporter/Ion channel |
Ajmaline (Cardiorythmine) 是一种钠通道阻断剂,属于1A 类抗心律失常剂。Ajmaline 阻断 HERG 电流,在 HEK 细胞的 IC50为 1 μM,爪蟾卵母细胞的IC50为 42.3 μM。Ajmaline 在室性心动过速方面具有研究价值。 | |||
TN5235 |
Vinorine
|
Others | Others |
Vinorine is a direct biosynthetic precursor along the complex pathway to the monoterpenoid indole alkaloid ajmaline, an antiarrhythmic drug from the Indian medicinal plant Rauvolfia serpentina. |