G 蛋白偶联受体 (GPCR)是一大类进化相关的蛋白质,是细胞表面受体,可检测细胞外分子并激活细胞反应。G 蛋白偶联受体仅存在于真核生物中,包括酵母和鞭毛虫。结合和激活这些受体的配体包括光敏化合物、气味、信息素、激素和神经递质等。G蛋白偶联受体与许多疾病有关。例如精神疾病、代谢疾病、免疫疾病、心血管疾病、炎症、感觉障碍和癌症。因此GPCR是一个重要的药物靶点,在FDA批准的所有药物中,约有34% 靶向该家族的108个成员。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-01365 | CD97 Protein, Human, Recombinant (His)
CD97 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
CD97 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.6 kDa and the accession number i... | |||
TMPY-01683 | CD97 Protein, Human, Recombinant (hFc)
CD97 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
CD97 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 68.2 kDa and the accession number i... | |||
TMPY-01797 | Frizzled 10 Protein, Mouse, Recombinant (hFc)
Frizzled 10 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession num... | |||
TMPY-01798 | Frizzled 10 Protein, Mouse, Recombinant (His)
Frizzled 10 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession n... | |||
TMPY-02037 | TSC22D1 Protein, Mouse, Recombinant (His)
TSC22D1 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
TSC22D1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.8 kDa and the accession nu... | |||
TMPY-02276 | GPR56 Protein, Human, Recombinant (His)
GPR56 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
ADGRG1 (Adhesion G Protein-Coupled Receptor G1, also known as GPR56) is a Protein Coding gene. GPR56 is a member of an adhesion G protein-coupled receptor family... | |||
TMPY-02400 | TSC22D1 Protein, Human, Recombinant (His)
TSC22D1 Protein, Human, Recombinant (His)
|
Human | E. coli |
TSC22D1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.2 kDa and the accession nu... | |||
TMPY-02717 | GPR37 Protein, Human, Recombinant (His)
GPR37 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family compris... | |||
TMPY-02837 | GPR114 Protein, Human, Recombinant (hFc)
GPR114 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture which consists of seven transmembrane dom... | |||
TMPY-03293 | Frizzled 5 Protein, Mouse, Recombinant (hFc)
Frizzled 5 Protein, Mouse, Recombinant (hFc)
|
Mouse | CHO Cells |
Frizzled 5 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession numbe... | |||
TMPY-03310 | Frizzled 4 Protein, Rat, Recombinant (hFc)
Frizzled 4 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known ... | |||
TMPY-03860 | Endothelin B Receptor Protein, Human, Recombinant (mFc)
Endothelin B Receptor Protein, Human, Recombinant (mFc)
|
Human | HEK293 Cells |
Endothelin B Receptor Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.4 kDa and the a... | |||
TMPY-04140 | Frizzled 10 Protein, Human, Recombinant (hFc)
Frizzled 10 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.8 kDa and the accession n... | |||
TMPY-04147 | Frizzled 10 Protein, Human, Recombinant (His)
Frizzled 10 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.5 kDa and the accession n... | |||
TMPY-04270 | GPR133 Protein, Human, Recombinant (His)
GPR133 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
ADGRD1 (Adhesion G Protein-Coupled Receptor D1, also known as GPR133) is a Protein Coding gene. 4 alternatively spliced human isoforms have been reported. ADGRD1... | |||
TMPY-04271 | Frizzled 6 Protein, Human, Recombinant (His)
Frizzled 6 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Frizzled 6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession nu... | |||
TMPY-04302 | Frizzled 4 Protein, Human, Recombinant (His)
Frizzled 4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known ... | |||
TMPY-04633 | Frizzled 2 Protein, Mouse, Recombinant (hFc)
Frizzled 2 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and... | |||
TMPY-05489 | Frizzled 5 Protein, Human, Recombinant (hFc)
Frizzled 5 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Frizzled 5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession nu... | |||
TMPY-05808 | Renin Protein, Human, Recombinant (R66K, His)
Renin Protein, Human, Recombinant (R66K, His)
|
Human | HEK293 Cells |
Renin Protein, Human, Recombinant (R66K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.74 kDa and the accession ... |