Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T18601 | Desmethyl-QCA276
化合物 T18601
|
2126819-55-2 | 98% |
|
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, ... | ||||
T18650 | Ch55-O-C3-NH2
化合物 T18650
|
144298-98-6 | 98% |
|
Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts wi... | ||||
T13843 | PROTAC IRAK4 ligand-1
化合物 T13843
|
2357108-39-3 | 98% |
|
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4. | ||||
T10320 | Androgen receptor antagonist 1
化合物 T10320
|
1338812-36-4 | 98% |
|
Androgen receptor antagonist 1 is an orally available full androgen receptor antagonist (IC50: 59 nM). It can be used in the synthesis of PROTAC AR degraders, wh... | ||||
T13888 | SLF
化合物 T13888
|
195513-96-3 | 98% |
|
SLF is a synthetic ligand for FK506-binding protein (FKBP)( with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12). SLF can be used in the synt... | ||||
T10345 | Apcin-A
化合物 T10345
|
1683617-62-0 | 98% |
|
Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be us... | ||||
T12558 | PROTAC BET-binding moiety 2
化合物 T12558
|
916493-82-8 | 98% |
|
PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor. | ||||
T12905 | SI-109
化合物 T12905
|
T12905 | 98% |
|
SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity. | ||||
T17940 | Estrone-N-O-C1-amido
化合物 T17940
|
138219-84-8 | 98% |
|
Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-... | ||||
T10734L | CDK ligand for PROTAC hydrochloride
化合物 T10734L
|
T10734L | 98% |
|
CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders. | ||||
T13841 | PROTAC Her3-binding moiety 1
化合物 T13841
|
1603845-36-8 | 98% |
|
PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC. | ||||
T13086 | I-BET762 carboxylic acid
化合物 T13086
|
1300019-38-8 | 98% |
|
I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1). | ||||
T12557 | PROTAC BET-binding moiety 1
化合物 T12557
|
2093387-77-8 | 98% |
|
PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors | ||||
T18053 | Ipatasertib-NH2
化合物 T18053
|
1001382-14-4 | 98% |
|
Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), ... | ||||
T13914 | SLF-amido-C2-COOH
化合物 T13914
|
1092369-24-8 | 98% |
|
SLF-amido-C2-COOH is a synthetic ligand for FKBP (SLF), and can be used in the synthesis of PROTACs. | ||||
T18611 | AP1867-2-(carboxymethoxy)
化合物 T18611
|
2230613-03-1 | 98% |
|
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molec... | ||||
T13915 | PROTAC BRD9-binding moiety 1
化合物 T13915
|
2097512-23-5 | 98% |
|
PROTAC BRD9-binding moiety 1 that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC. | ||||
T18592 | Imatinib carbaldehyde
化合物 T18592
|
1436868-85-7 | 98% |
|
Imatinib carbaldehyde (also known as CGP-57148B carbaldehyde) is a compound derived from Imatinib, an inhibitor of the ABL protein. Imatinib carbaldehyde binds t... | ||||
T10743 | CDK9-IN-11
化合物 T10743
|
2748368-15-0 | 98% |
|
CDK9-IN-11 是一种有效的CDK9抑制剂,可作为 PROTAC CDK9 Degrader-1 的配体。 | ||||
T10522 | BET-IN-6
化合物 T10522
|
2570470-39-0 | 98% |
|
BET-IN-6 是一种有效且高亲和力的BRD2/BRD4抑制剂。BET-IN-6 是靶蛋白 BRD2/4 的配体,可用于合成 PROTAC BRD2/BRD4 degrader-1 。 |