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Tau Protein, Human, Recombinant (His)

产品编号 TMPY-03425

别名: PPND, FTDP-17, MTBT1, DDPAC, MAPTL, MTBT2, microtubule-associated protein tau, PPP1R103, MAPT, MSTD, TAU

MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs.

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Tau Protein, Human, Recombinant (His) Chemical Structure

Tau Protein, Human, Recombinant (His), CAS N/A

规格	价格/CNY	货期
50 μg	￥ 3,820	现货
100 μg	￥ 6,530	5日内发货
200 μg	￥ 11,130	5日内发货
500 μg	￥ 22,510	5日内发货

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其他形式的 Tau Protein, Human, Recombinant (His):

Microtubule-associated protein tau (26-44)
询价
Tau-D Protein, Human, Recombinant (His)
询价
Tau-F Protein, Human, Recombinant
询价

选择批次

纯度: 89.2%

更多批次查询请联系客服

生物活性

化学信息

存储 & 溶解度

参考文献

产品描述

别名	PPND, FTDP-17, MTBT1, DDPAC, MAPTL, MTBT2, microtubule-associated protein tau, PPP1R103, MAPT, MSTD, TAU
分子量	38.7 kDa (predicted)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

计算器

摩尔浓度计算器

稀释计算器

配液计算器

分子量计算器

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参考文献

1. Harada A, et al. (1994) Altered microtubule organization in small-calibre axons of mice lacking tau protein. Nature. 369(6480):488-91. 2. Weingarten MD, et al. (1975) A protein factor essential for microtubule assembly. Proc Natl Acad Sci. 72(5):1858-62. 3. Goedert M, et al. (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3(4): 519-26.

剂量换算

对于不同动物的给药剂量换算，您也可以参考 更多...

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10 只，您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL)，如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法：取 50 μL DMSO 主液，加入 300 μL PEG300，混匀澄清，再加 50 μL Tween 80，混匀澄清，再加 600 μL ddH2O, 混匀澄清。

第一步：请输入动物实验的基本信息

剂量

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第二步：请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。

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