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MDGA2 Protein, Mouse, Recombinant (His)

MDGA2 Protein, Mouse, Recombinant (His)

产品编号 TMPY-01620
别名: 6720489L24Rik, Adp, MAM domain containing glycosylphosphatidylinositol anchor 2, Mamdc1, 9330209L04Rik

MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance. 在相同实验条件下,摩尔浓度相同的化合物盐形式与游离态具有相同的生物活性,但盐形式 Adenosine 5'-diphosphate 的水溶性和稳定性通常比游离态更好。

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MDGA2 Protein, Mouse, Recombinant (His) Chemical Structure
MDGA2 Protein, Mouse, Recombinant (His), CAS N/A
规格 价格/CNY 货期 数量
50 μg ¥ 3,820 5日内发货

MDGA2 Protein, Mouse, Recombinant (His) 的其他形式现货产品:

Adenosine 5'-diphosphate
其他形式的 MDGA2 Protein, Mouse, Recombinant (His):
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: MDGA2 Protein, Mouse, Recombinant (His) (TMPY-01620)
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生物活性
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参考文献
产品描述 MAM domain-containing glycosylphosphatidylinositol anchor protein 2, also known as MAM domain-containing protein 1, MDGA2, and MAMDC1, is a cell membrane protein that contains six Ig-like (immunoglobulin-like) domains and one MAM domain. Analyses of the full-length coding region of MDGA1 and MDGA2 indicate that they encode proteins that comprise a novel subgroup of the Ig superfamily and have a unique structural organization consisting of six immunoglobulin (Ig)-like domains followed by a single MAM domain. Biochemical characterization demonstrates that MDGA1 and MDGA2 proteins are highly glycosylated and that MDGA1 is tethered to the cell membrane by a GPI anchor. The MDGAs are differentially expressed by subpopulations of neurons in both the central and peripheral nervous systems, including neurons of the basilar pons, inferior olive, cerebellum, cerebral cortex, olfactory bulb, spinal cord, and dorsal root and trigeminal ganglia. The similarity of MDGAs to other Ig-containing molecules and their temporal-spatial patterns of expression within restricted neuronal populations, for example migrating pontine neurons and D1 spinal interneurons, suggest a role for these novel proteins in regulating neuronal migration, as well as other aspects of neural development, including axon guidance.
别名 6720489L24Rik, Adp, MAM domain containing glycosylphosphatidylinositol anchor 2, Mamdc1, 9330209L04Rik
分子量 103 kDa (predicted)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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TargetMol Library Books参考文献

1. Litwack,ED. et al., 2004, Mol Cell Neurosci. 25 (2): 263-74. 2. Hellquist, A. et al., 2009, PLoS One. 4 (12): e8037. 3. Sano,S. et al., 2009, Genesis. 47 (8):505-13. 4. Bucan, M. et al., 2009, PLoS Genet. 5 (6):e1000536.

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体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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Keywords

MDGA2 Protein, Mouse, Recombinant (His) 6720489L24Rik Adp MAM domain containing glycosylphosphatidylinositol anchor 2 Mamdc1 9330209L04Rik Inhibitor inhibitor inhibit

 

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