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HRSP12 Protein, Human, Recombinant (His)

HRSP12 Protein, Human, Recombinant (His)

产品编号 TMPJ-01007
别名: p14.5, UK114 Antigen Homolog, Heat-Responsive Protein 12, Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, HRSP12, PSP

Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.

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HRSP12 Protein, Human, Recombinant (His) Chemical Structure
HRSP12 Protein, Human, Recombinant (His), CAS N/A
规格 价格/CNY 货期 数量
10 μg ¥ 620 5日内发货
50 μg ¥ 1,720 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 17,400 5日内发货
产品目录号及名称: HRSP12 Protein, Human, Recombinant (His) (TMPJ-01007)
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存储 & 溶解度
产品描述 Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
别名 p14.5, UK114 Antigen Homolog, Heat-Responsive Protein 12, Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, HRSP12, PSP
分子量 16 KDa (reducing condition)

存储

store at low temperature | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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Keywords

HRSP12 Protein, Human, Recombinant (His) Ribonuclease UK-114 HRSP 12 p14.5 UK114 Antigen Homolog Heat-Responsive Protein 12 Ribonuclease UK114 14.5 kDa Translational Inhibitor Protein Ribonuclease UK 114 HRSP-12 HRSP12 PSP Inhibitor inhibitor inhibit

 

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