Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 1,950 | 5日内发货 | ||
5 mg | ¥ 2,890 | 5日内发货 | ||
10 mg | ¥ 4,160 | 5日内发货 | ||
1 mL * 10 mM (in DMSO) | ¥ 3,180 | 5日内发货 |
产品描述 | DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro. |
体外活性 | In vitro, DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P ≤ 0.05). In contrast, TCA (up to 500 μM) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF-α release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures. |
分子量 | 216.09 |
分子式 | C5H7Cl2NO2S |
CAS No. | 13419-46-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 23 mg/mL (106.44 mM)
H2O: 1.034 mg/mL (4.79 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO / H2O | 1 mM | 4.6277 mL | 23.1385 mL | 46.277 mL | 115.6925 mL |
DMSO | 5 mM | 0.9255 mL | 4.6277 mL | 9.2554 mL | 23.1385 mL |
10 mM | 0.4628 mL | 2.3139 mL | 4.6277 mL | 11.5693 mL | |
20 mM | 0.2314 mL | 1.1569 mL | 2.3139 mL | 5.7846 mL | |
50 mM | 0.0926 mL | 0.4628 mL | 0.9255 mL | 2.3139 mL | |
100 mM | 0.0463 mL | 0.2314 mL | 0.4628 mL | 1.1569 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
DCVC 13419-46-0 Inhibitor inhibitor inhibit