Powder: -20°C for 3 years | In solvent: -80°C for 1 year
17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persian sturgeon oocytes has been shown to effectively induce germinal vesicle breakdown, an essential step during oocyte maturation.1 Gonadotropin-releasing hormone and the gonadotropins, follicle-stimulating hormone and luteinizing hormone, have been shown to stimulate the production of 17α,20β-DHP either in vivo or in vitro.[2] 17α,20β-DHP has also been reported to influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts.[1]
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 770 | 35日内发货 | ||
5 mg | ¥ 2,270 | 35日内发货 | ||
10 mg | ¥ 3,970 | 35日内发货 |
产品描述 | 17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persian sturgeon oocytes has been shown to effectively induce germinal vesicle breakdown, an essential step during oocyte maturation.1 Gonadotropin-releasing hormone and the gonadotropins, follicle-stimulating hormone and luteinizing hormone, have been shown to stimulate the production of 17α,20β-DHP either in vivo or in vitro.[2] 17α,20β-DHP has also been reported to influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts.[1] |
别名 | 17α,20β-dihydroxy Progesterone, 17α,20β-DHP, 17α,20β-Dihydroxy-4-pregnen-3-one |
分子量 | 332.48 |
分子式 | C21H32O3 |
CAS No. | 1662-06-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: 1 mg/mL
Acetonitrile: 1 mg/mL
Ethanol: 1 mg/mL
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
17α,20β-Dihydroxy-4-pregnen-3-one 1662-06-2 17alpha,20beta-DHP 17α,20β-dihydroxy Progesterone 17alpha,20beta-Dihydroxy-4-pregnen-3-one 17α,20β Dihydroxy 4 pregnen 3 one 17α,20β-DHP 17a,20b-Dihydroxy-4-pregnen-3-one 17alpha,20beta-dihydroxy Progesterone 17a,20b-DHP 17a,20b-dihydroxy Progesterone 17α,20βDihydroxy4pregnen3one Inhibitor inhibitor inhibit