Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18732 |
sulfo-SPDB
|
Others | Others |
sulfo-SPDB is a cleavable linker vital in ADC synthesis. sulfo-SPDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness. | |||
T18703 |
SPDB-sulfo
|
Others | Others |
SPDB-sulfo, a glutathione-cleavable linker, is utilized in the development of antibody-drug conjugates (ADCs) [1]. | |||
T40762 |
NO2-SPDB-sulfo
NO2-SPDB-sulfo |
||
NO2-SPDB-sulfo is a cleavable linker vital in ADC synthesis. NO2-SPDB-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness. | |||
T40765 |
DMAC-SPDB-sulfo
|
||
DMAC-SPDB-sulfo is a cleavable linker vital in ADC synthesis. DMAC-SPDB-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness. | |||
T18730 |
sulfo-SPDB-DM4
|
Others | Others |
Sulfo-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) that employs the maytansine-based payload (DM4, an antitubulin agent) connected through the sulfo-SPDB linker. | |||
T81060 |
Sulfo-SPDB-DGN462
|
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Sulfo-SPDB-DGN462为一种ADC活性连接剂,毒素DGN462通过可裂解的Sulfo-SPDB linker偶联形成。DGN462是一种DNA烷基化剂,对抗肿瘤(如急性髓系白血病[AML])表现出有效性。 |