30
5
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1616 |
Cefotiam hydrochloride
盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefotiam hydrochloride (SCE-963 hydrochloride) 是一种肠外头孢菌素类广谱抗生素,对革兰氏阳性菌和革兰氏阴性菌有活性。 | |||
T6386 |
Ampicillin sodium
氨苄西林钠,Domicillin,D-(-)-α-Aminobenzylpenicillin sodium salt,Penialmen,Citteral |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin sodium (Domicillin) 是Ampicillin 的钠盐形式,是Ampicillin 的广谱半合成衍生物。它通过与青霉素结合蛋白结合来抑制细菌细胞壁的合成,从而抑制肽聚糖的合成,肽聚糖是细菌细胞壁的关键成分。 | |||
T5022 |
Ceforanide
|
Antibacterial; Antibiotic | Microbiology/Virology |
Ceforanide 是一种头孢菌素,可静脉或肌肉给药。它在体外具有一系列抗菌活性。 | |||
T1063 |
Ticarcillin disodium
Ticarpen,Ticarcillin disodium salt,替卡西林二钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ticarcillin disodium (Ticarpen) 主要用于抗革兰氏阴性菌, 特别是绿脓杆菌, 也是少数可研究嗜麦芽感染的抗生素。 | |||
T0953 |
Cefazolin sodium
Ancef,头孢唑啉钠,头孢唑林钠,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Cefazolin sodium (cephazolin sodium) salt 是一种头孢类抗生素, 可研究多种细菌感染。 | |||
T1005L |
Amoxicillin trihydrate
Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,阿莫西林三水物,Moxaline trihydrate |
Antibacterial; Antibiotic | Microbiology/Virology |
Amoxicillin trihydrate (Moxaline trihydrate) 是一种中谱β内酰胺抗菌素。 | |||
T6437 |
Cefoperazone
头孢哌酮,Cefob,Medocef |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefoperazone (Medocef) 是一种半合成的头孢菌素,有抗菌活性。 | |||
T0932 |
Cefixime
FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefixime (FR-17027) 是一种头孢菌素类抗生素, 可研究一些细菌感染。 | |||
T1213 |
Piperacillin sodium
哌拉西林钠,Sodium piperacillin,CL227193,Piperacillin sodium salt |
Antibacterial; Antibiotic | Microbiology/Virology |
Piperacillin sodium salt(CL227193) )是一种β-内酰胺类广谱抗生素。 | |||
T1005 |
Amoxicillin
Amoxycillin,阿莫西林 |
Antibacterial; Antibiotic | Microbiology/Virology |
Amoxicillin (Amoxycillin) 是一种具有广谱抗菌活性和良好口服吸收的抗生素。 | |||
T1228 |
Cefonicid sodium
Monocid sodium,头孢尼西钠,Cefonicid disodium salt |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefonicid sodium (Monocid sodium) 是一种广谱头孢类抗生素, 能抑制细菌细胞壁的形成。 | |||
T5024 |
Cefotiam Hexetil Hydrochloride
盐酸头孢替安酯,头孢替安海替酯盐酸盐 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefotiam hexetil hydrochloride 是一种可口服头孢菌素,是抗生素 cefotiam 的前药,但无抗菌作用。 | |||
T1224 |
Cefuroxime sodium
Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素,增加了对 β-内酰胺酶的稳定性。 | |||
T1122 |
Cephalothin sodium
头孢噻吩钠,Cefalotin sodium,Cephalothin,Cefalotin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cephalothin sodium (Cefalotin) 是一种头孢类抗生素, 具有广泛的抗菌活性,抑制革兰氏阳性和阴性菌。 | |||
T27705 |
K103 Hydrochloride
K103,K-103,2PIQ,K 103 |
||
K103 Hydrochloride, an inhibitor of peptidoglycan synthesis, targets the lipid II precursor. | |||
T25767 |
Lysobactin
Katanosin A, 7-L-isoleucine-,Katanosin B |
||
Lysobactin, also known as katanosin B, is an effective antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis. | |||
T28288 |
Pacidamycin I
A-68567,A 68567,A68567 |
||
Pacidamycin I is an antimicrobial nucleoside antibiotics. Pacidamycin I inhibits translocase I, a key enzyme in peptidoglycan assembly. | |||
T27390 | Friulimicin B | ||
Friulimicin B is a peptidoglycan synthesis inhibitor with excellent activity against gram-positive pathogens through cell wall interruption. | |||
T70020 | Vancomycin monohydrochloride | ||
Vancomycin monohydrochloride is an amphoteric glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to peptidoglycan. | |||
T71881 |
Bromophenol red
|
||
Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan. | |||
T37682 |
3-hydroxy Tridecanoic Acid
|
||
3-hydroxy Tridecanoic acid is a 13-carbon saturated fatty acid found in bacterial lipopolysaccharides (LPS). It can be used as an internal standard to detect markers of microorganisms in complex samples, including 3-hydroxy fatty acids found in LPS-containing bacteria and muramic acid found in bacterial cell wall peptidoglycan. | |||
T74866 | Antibacterial agent 116 | ||
Antibacterial agent 116 是一种含二苯甲酮的水杨酰苯胺类化合物。Antibacterial agent 116 能抑制肽聚糖的形成而具有较强的抗菌活性。Antibacterial agent 116 可作为光亲和探针标记 Acinetobacter baumannii 的青霉素结合蛋白 (PBP1b),干扰肽聚糖链的生长,阻断其增殖。 | |||
T70621 |
Cefditoren Pivoxil HCl
|
||
Cefditoren Pivoxil is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil is a prodrug that is rapidly hydrolyzed by intestinal esterases during absorption to the microbiologically active cefditoren, an active aminothiazolyl cephalosporin. Cefditoren inactivates penicillin binding proteins (PBPs) thereby interfering with peptidoglycan synthesis and inhibiting bacterial cell wall synthesis. | |||
T69873 |
Cefdinir monohydrate
|
||
Cefdinir monohydrate is the salt form of Cefdinir (free base), a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidog... | |||
T74555 |
EDA-DA
|
||
EDA-DA 是一种 N 末端标记的二肽探针,可用于标记细菌的肽聚糖 (PG)。肽聚糖 (PG) 是绝大多数细菌细胞壁中的一种基本结构,对于分裂和维持细胞形状和静水压力至关重要。 | |||
T69266 | Cefcanel free acid | ||
Cefcanel is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcanel is active against the species E. coli, K. aerogenes and Proteus mirabilis; H. influenzae and M. catarrhalis has reasonable susceptibility. Cefcanel inhibits 90% of S. aureus strains at 2 µg/ml, irrespective of the presence of a β-lactamase. Cefcanel binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the te... | |||
T37874 |
Feglymycin
|
||
Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replication in H9 cells (IC50 = ~5 μM). Feglymycin is also active against clinical isolates of HIV-1 from clades A-D, A/E, and G (EC50s = 0.5-6.7 μM). It interacts with gp120 and inhibits HIV-1 NL4.3 binding to human soluble CD4 (EC50 = 4.4 μM) and to CD4+ SupT1 T cells by 74.5% when us... | |||
T83940 |
sCy5DL-amide
|
||
sCy5DL-amide是一种荧光D-氨基酸,适用于标记多种细菌的肽聚糖,包括革兰氏阳性菌、革兰氏阴性菌和分枝杆菌。特别适合于革兰氏阳性的B.subtilis的标记。使用sCy5DL-amide标记的细菌可通过单分子定位显微镜技术(SMLM;也称为PALM或STORM)进行成像。激发/发射最大值为646/666 nm。 | |||
T69966 |
Roxadustat-d5
|
||
Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ... | |||
T38301 |
Click N-Acetylmuramic acid - alkyne
|
||
Derivative of N-acetylmuramic acid (NAM) component of bacterial peptidoglycans. Incorporated into bacterial peptidoglycans during biosynthesis. Suitable for fluorescent labeling of peptidoglycans when 'click'-conjugated to a fluorescent dye. Liang et al (2017) Metabolic labelling of the carbohydrate core in bacterial peptidoglycan and its applications. Nat.Commun. 8 15015 PMID:28425464 |DeMeester et al (2018) Synthesis of functionalized N-Acetyl muramic acids to probe bacterial cell wall recycli... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1722 |
Hamamelitannin
|
Antifection | Microbiology/Virology |
Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚,是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。 | |||
T1589 |
D-Cycloserine
RO-1-9213,D-环丝氨酸 |
Others; Antibacterial; Antibiotic; iGluR | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; Others |
D-Cycloserine (RO-1-9213) 是一种抗生素,靶向细菌细胞壁肽聚糖生物合成酶。它是一种NMDA 部分激动剂,可以改善认知功能,可研究耐多药结核病。 | |||
T1226 |
Bacitracin
Albac,Ziba-RX,杆菌肽 |
Antibacterial; Antibiotic | Microbiology/Virology |
Bacitracin (Ziba-RX) 是一种用于葡萄球菌感染的多肽抗生素。它通过与焦磷酸十一癸烯基结合,起抑制细胞壁生物合成作用。 | |||
T4889 |
2,6-Diaminoheptanedioic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。 | |||
T36990 |
Moenomycin Complex
|
||
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1] |