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Search Results for " pentylenetetrazole seizure mice "

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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T37950 2-(Isopentylamino)naphthalene-1,4-dione

2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively). 1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential tr...
T37847 Zonisamide-13C2,15N

Zonisamide-13C2,15N

Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

化合物

2-(Isopentylamino)naphthalene-1,4-dione
Cat.No: T37950
Synonym:
Target:
Zonisamide-13C2,15N
Cat.No: T37847
Synonym: Zonisamide-13C2,15N
Target:
Cat. No. Product Name Target Signaling Pathways
T0983 Penicillamine

青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Antibiotic Microbiology/Virology
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。

天然产物

Penicillamine
Cat.No: T0983
Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine
Target: Antibiotic
TargetMol Loading
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