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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8490	Butoconazole 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole,布康唑	Antifungal	Microbiology/Virology
	Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) 是一种咪唑类抗真菌药物，可治疗白色念珠菌引起的阴道感染。它可通过抑制类固醇起抗菌作用。
T38376	2-O-(α-D-Glucopyranosyl)glycerol 2-alphaGG	Others	Others
	2-O-(α-D-Glucopyranosyl)glycerol (2-alphaGG) 存在于少数细菌和生长在恶劣环境中的植物中，可通过增加渗透压反应来延长出芽酵母的寿命和红孢子虫的寿命。
T65167	EDTA copper(II) disodium salt	Antibiotic	Microbiology/Virology
	EDTA copper(II) disodium salt 是一种金属螯合剂，具有抗菌、抗炎、抗氧化活性，可减缓金属离子造成的损伤，可维持蛋白纯化过程中的渗透压，可用于研究神经系统疾病。
T35449	α-(difluoromethyl)-DL-Arginine DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine	Others	Others
	α-(difluoromethyl)-DL-Arginine (RMI 71897) 是一种酶激活的、不可逆的大肠杆菌(Ki = 800 μM)、铜绿假单胞菌和肺炎克雷伯菌精氨酸脱羧酶抑制剂。在0.01 mM 时，它已被证明可以防止渗透胁迫诱导的燕麦叶片细胞精氨酸脱羧酶活性和腐胺合成的增加。当α-(difluoromethyl)-DL-Arginine 与多种多胺类似物联用时，能在10 mM 的最低浓度下抑制克氏锥虫在哺乳动物宿主细胞中的生长，并在T 细胞受体α缺陷小鼠模型中阻止小锥虫的生长。
T33572	N-Acetylglutaminylglutamine amide NAGGN
	N-Acetylglutaminylglutamine amide, as an unusual dipeptide, can be accumulated during osmotic stress in Rhizobium meliloti.
T70954	SP-187 HCl
	SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium.

化合物

Butoconazole

Cat.No: T8490

Synonym: 1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole,布康唑

Target: Antifungal

2-O-(α-D-Glucopyranosyl)glycerol

Cat.No: T38376

Synonym: 2-alphaGG

Target: Others

EDTA copper(II) disodium salt

Cat.No: T65167

Synonym:

Target: Antibiotic

α-(difluoromethyl)-DL-Arginine

Cat.No: T35449

Synonym: DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine

Target: Others

N-Acetylglutaminylglutamine amide

Cat. No.	Product Name	Target	Signaling Pathways
T5239	Cholesteryl sulfate sodium Cholesterol 3-Sulfate Sodium Salt,胆固醇硫酸酯钠盐,Sodium Cholesteryl Sulfate	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) 是内源性代谢产物的一种。
T5086	Pharmatose DCL 14 D-乳糖一水合物,D-Lactose monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Pharmatose DCL 14 (D-Lactose monohydrate) 是内源性代谢产物的一种。
T4959	DL-Mannitol 甘露醇,Mannitol	Others	Others
	DL-Mannitol 是由 D-mannitol 与 L-mannitol 通过 L-mannono-1, Clactone 还原得到的。
T5663	α-Lactose D-乳糖单水合物,Lactose	Others	Others
	α-Lactose 是牛奶中的主要的糖。它一般以 α 和 β 两个异构体的形式存在，其中α 形式通常以一水合物的形式结晶。
T3S1319	(+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine,木兰花碱	Others; Antifungal	Microbiology/Virology; Others
	(+)-Magnoflorine (Thalictrin) 是从 Acoruscalamus 中分到的一种阿朴啡生物碱，可以减少 C. albicans 生物膜的形成，具有抗真菌、抗氧化、抗糖尿病、镇静和抗焦虑的作用。
TN2201	Semilicoisoflavone B	Others	Others
	Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia.