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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T12004 Meropenem trihydrate

美罗培南三水合物,SM 7338 trihydrate

Antibacterial; Antibiotic Microbiology/Virology
Meropenem trihydrate (SM 7338 trihydrate) 是一种碳青霉烯抗生素,具有广谱抗菌活性。它对敏感和耐药的杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL), 淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL)和流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 具有活性。
T0868L Cefepime

Cefepime is an antibiotic. Cefepime has been shown to be effective against febrile neutropenia.
T69516 Thenalidine tartrate

Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug. It was withdrawn from the US, Canadian, and UK markets due to a risk of neutropenia. Thenalidine is an antagonist of the H1-receptor.
T61581 LasR-IN-2

LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in cystic fibrosis (CF) [1].
T77172 Eflapegrastim

Eflapegrastim 是一种人源化IgG4单抗 ,也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化,维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。
T14493 Balapiravir

R1626,Ro 4588161

Others Others
Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (m

化合物

Meropenem trihydrate
Cat.No: T12004
Synonym: 美罗培南三水合物,SM 7338 trihydrate
Target: Antibacterial, Antibiotic
Cefepime
Cat.No: T0868L
Synonym:
Target:
Thenalidine tartrate
Cat.No: T69516
Synonym:
Target:
LasR-IN-2
Cat.No: T61581
Synonym:
Target:
Eflapegrastim
Cat.No: T77172
Synonym:
Target:
Balapiravir
Cat.No: T14493
Synonym: R1626,Ro 4588161
Target: Others
Cat. No. Product Name Target Signaling Pathways
T0224 Meropenem

美罗培南,SM 7338

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
Meropenem (SM 7338) 是一种具有广谱抗菌活性的碳青霉烯抗生素,对敏感和耐药的淋病奈瑟氏球菌,流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL,0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。

天然产物

Meropenem
Cat.No: T0224
Synonym: 美罗培南,SM 7338
Target: Others, Antibacterial, Antibiotic
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