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Cat. No. Product Name Target Signaling Pathways
T39771 nAChR agonist CMPI hydrochloride

nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) of nAChR containing a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of (α4) 3 (β2) 2 nAChR to ACh (10 μM) with an EC 50 of 0.26 μM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity.

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nAChR agonist CMPI hydrochloride
Cat.No: T39771
Synonym:
Target:
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