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Cat. No. | Product Name | Target | Signaling Pathways |
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T14496 |
BAMB-4
ITPKA-IN-C14 |
Others | Others |
BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂,在ADP-Glo 实验中的IC50值为37uM。 | |||
T74087 | 2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium | ||
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium 是 ATP 类似物,对 poly(AU) 合成有显著的抑制效果。 | |||
T37248 |
Pantothenate Kinase Inhibitor
|
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Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to... | |||
T61049 | AChE-IN-11 | ||
AChE-IN-11 (compound 5C) 可用于阿尔茨海默病的研究,它具有神经保护作用和良好的抗氧化活性 (ORAC = 2.5 eq) 。AChE-IN-11 是一种很好的多功能剂,其对于AChE、MAO-B 和 BACE1 的 IC 50 值分别为 7.9 μM、9.9 μM 和 8.3 μM。AChE-IN-11 具有混合型 AChE 抑制作用,可与结合AChE 的 CAS 和 PAS 结合。AChE-IN-11 也是一种选择性金属离子螯合剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMA2563 |
Pedalitin
|
Tyrosinase | Proteases/Proteasome |
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors. |