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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T14496 BAMB-4

ITPKA-IN-C14

Others Others
BAMB-4 (ITPKA-IN-C14) 是一种新型的膜渗透型ITPKA 抑制剂,在ADP-Glo 实验中的IC50值为37uM。
T74087 2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium

2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium 是 ATP 类似物,对 poly(AU) 合成有显著的抑制效果。
T37248 Pantothenate Kinase Inhibitor

Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to...
T61049 AChE-IN-11

AChE-IN-11 (compound 5C) 可用于阿尔茨海默病的研究,它具有神经保护作用和良好的抗氧化活性 (ORAC = 2.5 eq) 。AChE-IN-11 是一种很好的多功能剂,其对于AChE、MAO-B 和 BACE1 的 IC 50 值分别为 7.9 μM、9.9 μM 和 8.3 μM。AChE-IN-11 具有混合型 AChE 抑制作用,可与结合AChE 的 CAS 和 PAS 结合。AChE-IN-11 也是一种选择性金属离子螯合剂。

化合物

BAMB-4
Cat.No: T14496
Synonym: ITPKA-IN-C14
Target: Others
2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium
Cat.No: T74087
Synonym:
Target:
Pantothenate Kinase Inhibitor
Cat.No: T37248
Synonym:
Target:
AChE-IN-11
Cat.No: T61049
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TMA2563 Pedalitin

Tyrosinase Proteases/Proteasome
Pedalitin is a mixed-type inhibitor of tyrosinase. In the assay of α-glucosidase inhibition, rosmarinic acid is a competitive inhibitor, whereas both methyl rosmarinate and Pedalitin are mixed-type inhibitors.

天然产物

Pedalitin
Cat.No: TMA2563
Synonym:
Target: Tyrosinase
TargetMol Loading
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