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Cat. No. | Product Name | Target | Signaling Pathways |
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T4989 |
Fosfomycin Tromethamine
|
Antibacterial; Antibiotic | Microbiology/Virology |
Fosfomycin tromethamine 是一种能透过血脑屏障的广谱抗生素,不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性,包括耐多药、广泛耐药和耐全药细菌。 | |||
T3131 |
Fosfomycin calcium
Phosphomycin calcium salt,Fosmicin,磷霉素钙 |
Antibacterial; Antibiotic | Microbiology/Virology |
Fosfomycin calcium (Phosphomycin calcium salt) 是一种能透过血脑屏障的广谱抗生素,不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性,包括耐多药、广泛耐药和耐全药细菌。 | |||
T77254 | Maltodextrin, dextrose equivalent 16.5-19.5 | ||
Maltodextrin(麦芽糊精),dextrose equivalent(葡萄糖当量)为16.5-19.5,可作为药用辅料。药用辅料,亦称药用助剂,非药物成分的化学物质,用于辅助药物制剂过程。此类辅料提升药物制剂的稳定性、溶解性及加工性,同时影响药物的吸收、分布、代谢及排泄(ADME)过程。 | |||
T68765 |
Spirorenone
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Spirorenone is an androstadienone derivative as a highly effective aldosterone antagonist. Spirorenone is 8.6 times as potent as spironolactone, but showed a lower affinity for the mineralocorticoid receptors. In phase I clinical trials Spirorenone was absorbed with a half-life of 20-30 min, achieving maximum concentrations of about 100 ng/ml (10 mg) and 260 ng/ml (40 mg) after 1-2 h. Disposition of the parent drug was biphasic with half-lives of 50-60 min (distribution) and 5-6 h (elimination).... | |||
T77228 | Polyoxyethylene Sorbitan Monostearate | ||
Polyoxyethylene Sorbitan Monostearate 是一种由饱和脂肪酸硬脂酸 (C18:0) 构成的酯,广泛应用作药用辅料,包括表面活性剂、乳化剂、增溶剂和润湿剂。作为药用助剂,其主要作用是改善药物制剂的稳定性、溶解性和加工性,同时对药物的吸收、分布、代谢和消除 (ADME) 过程具有影响。 | |||
T73620 | Poly(acrylic acid) | ||
Poly(acrylic acid) 通过吸附作用在金属表面形成保护层,有效抑制纯铸铝在酸性介质中的腐蚀现象。此外,Poly(acrylic acid) 还可作为药物制剂中的包衣材料、释放阻断剂等药用辅料使用。药用辅料,亦称药用助剂,是指在制药过程中,除药物活性成分外使用的其他化学物质。这些辅料通常作为非活性成分加入药物制剂中,旨在提升制剂的稳定性、溶解性及加工性。同时,药用辅料对药物的吸收、分布、代谢与排泄(ADME)过程也具有一定影响。 | |||
T37800 |
PF-04449613
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PF-04449613 is a phosphodiesterase 9A (PDE9A) inhibitor (IC50= 22 nM).1It is selective for PDE9A over PDE1C (IC50= >1,000 nM), as well as over a variety of other PDEs, inhibiting PDE2-8, -10, and -11 activity by less than 30% in a panel of enzymes, ion channels, and transporters at 1 μM but does inhibit the human dopamine transporter (DAT; Ki= 293 nM). PF-04449613 (0.1-100 mg/kg, s.c.) increases cerebrospinal fluid (CSF) levels of cyclic GMP (cGMP) in rats. Subcutaneous administration of PF-0444... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8262 |
Fosfomycin sodium
Fosfomycin Disodium,磷霉素钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Fosfomycin sodium 是一种能透过血脑屏障的广谱抗生素,不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性,包括耐多药、广泛耐药和耐全药的细菌。 |