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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T29650	ADDA
	ADDA is a non-proteinogenic amino acid existed in toxins produced by cyanobacteria.
T37118	ADP-Glucose (sodium salt) ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)
	ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.[1],[2] It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported in...
T82635	Cy-FBP/SBPase-IN-1
	Cy-FBP/SBPase-IN-1（compound S5）是一种针对蓝藻光合作用调节酶的Cy-FBP/SBPase抑制剂。该化合物能有效阻断卡尔文循环和光系统，从而减少蓝藻的光合效率。此外，Cy-FBP/SBPase-IN-1能抑制包括集胞藻PCC6803在内的蓝藻生长，并在人源细胞与斑马鱼模型中表现出良好的安全性。
T70244	JRN73958
	JRN73958 is an important precursor for the synthesis of scytonemin, also called Reduced scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, whi...
T70977	JMN13497
	JMN13497 is an precursor compound to for synthesis of scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive on...

化合物

ADP-Glucose (sodium salt)

Cat.No: T37118

Synonym: ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)

Cat. No.	Product Name	Target	Signaling Pathways
T22911	β-N-methylamino-L-alanine hydrochloride L-BMAA hydrochloride	Others	Others
	β-N-methylamino-L-alanine hydrochloride (L-BMAA hydrochloride) 是由蓝细菌产生的一种神经毒素，既有导致肌萎缩性侧索硬化症 (ALS) 以及其他可能的神经退行性疾病可能性。
T81795	Microcystin-WR
	Microcystin-WR为蓝藻代谢产物中的一种微囊藻毒素，对小鼠表现出肝脏毒性。
T70495	Scytonemin
	Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ...