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Cat. No. Product Name Target Signaling Pathways
T76163 Arylsulfatase

Arylsulfatase 是原核生物和真核生物的一类酶。Arylsulfatase 是一种硫酸酯酶,常用于生化研究。
T37437 C17 Ceramide (d18:1/17:0)

C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzyme replacement therapy for the genetic disease metachromatic leukodystrophy.
T38283 Tetracosanoyl-sulfatide

C24 3'-sulfo Galactosylceramide (d18:1/24:0)

Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mo...
T38183 C18 3'-sulfo Galactosylceramide (d18:1/18:0)

C18 3'-sulfo Galactosylceramide (d18:1/18:0)

C18 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. Levels of short-chain sulfatides, including C18 3'-sulfo galactosylceramide, decrease with age in mice and humans. It is increased in brain from mice with an arylsulfatase A deficiency (ASA-KO), particularly in lipid raft fractions. Plasma levels of C18 3'-sulfo galactosylceramide positively correlate with disability progression in patients with relapsing-remitting multiple sclerosis using the Expanded Disability ...
T38090 3'-sulfo Galactosylsphingosine (ammonium salt)

3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 μM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 μM, respectively. 3'-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) d...
T35639 Sulfatides (bovine) (sodium salt)

Sulfatides are endogenous sulfoglycolipids with various biological activities in the central and peripheral nervous systems, pancreas, and immune system. They are produced from the combination of ceramide and UDP-galactose in the endoplasmic reticulum followed by sulfation in the Golgi apparatus. The ceramide portion contains variable fatty acid chain lengths, which are tissue- and pathology-dependent. Sulfatides are primarily found in the myelin sheath of oligodendrocytes and Schwann cells, wit...

化合物

Arylsulfatase
Cat.No: T76163
Synonym:
Target:
C17 Ceramide (d18:1/17:0)
Cat.No: T37437
Synonym:
Target:
Tetracosanoyl-sulfatide
Cat.No: T38283
Synonym: C24 3'-sulfo Galactosylceramide (d18:1/24:0)
Target:
C18 3'-sulfo Galactosylceramide (d18:1/18:0)
Cat.No: T38183
Synonym: C18 3'-sulfo Galactosylceramide (d18:1/18:0)
Target:
3'-sulfo Galactosylsphingosine (ammonium salt)
Cat.No: T38090
Synonym:
Target:
Sulfatides (bovine) (sodium salt)
Cat.No: T35639
Synonym:
Target:
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