Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36331 |
Z-AEVD-FMK
Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone |
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Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2] | |||
T23555 |
Z-VEID-FMK
|
Others | Others |
When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluorometh |