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Cat. No. Product Name Target Signaling Pathways
T36331 Z-AEVD-FMK

Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 &#181M, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.[2]

化合物

Z-AEVD-FMK
Cat.No: T36331
Synonym: Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone
Target:
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