Cat. No. | Product Name | Target | Signaling Pathways |
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T68922 |
YM543 free base
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YM543 free base 为口服有效的钠-葡萄糖协同转运蛋白(SGLT) 2抑制剂,主要用于降低血糖水平,适用于糖尿病研究。 | |||
T29188 |
YM-543 trimethylamine
ASP 543,ASP-543,ASP543 |
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YM-543, a sodium-glucose transporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes. | |||
T70390 |
YM-543 choline
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YM-543, also known as ASP-543, is a selective SGLT2 inhibitor. Sodium-glucose cotransporter 2 (SGLT2) is a specifically expressed transporter in the kidney that plays an important role in renal glucose reabsorption, and its inhibition may present a novel therapeutic strategy for treating diabetes. YM543 potently and selectively inhibited mouse and human SGLT2 activities at nanomolar ranges. In vivo single oral administration of YM543 dose-dependently and significantly reduced blood glucose level... |