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Cat. No.	Product Name	Target	Signaling Pathways
T70390	YM-543 choline
	YM-543, also known as ASP-543, is a selective SGLT2 inhibitor. Sodium-glucose cotransporter 2 (SGLT2) is a specifically expressed transporter in the kidney that plays an important role in renal glucose reabsorption, and its inhibition may present a novel therapeutic strategy for treating diabetes. YM543 potently and selectively inhibited mouse and human SGLT2 activities at nanomolar ranges. In vivo single oral administration of YM543 dose-dependently and significantly reduced blood glucose level...
T29188	YM-543 trimethylamine ASP 543,ASP-543,ASP543
	YM-543, a sodium-glucose transporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.
T68922	YM543 free base
	YM543 free base 为口服有效的钠-葡萄糖协同转运蛋白(SGLT) 2抑制剂，主要用于降低血糖水平，适用于糖尿病研究。