Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03658 |
ETHE1 Protein, Human, Recombinant (His)
YF13H12,HSCO,ethylmalonic encephalopathy 1 |
Human | E. coli |
ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic en... |