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Cat. No. Product Name Target Signaling Pathways
T82260 Grisnilimab

WT1
Grisnilimab (WT1)为IgG2a亚型的单克隆抗体（抗CD7），与Wilms' tumor发病相关的肿瘤抑制因子。该抗体能够调控多个靶基因的转录活性，并可能涉及RNA的转录后修饰过程。
T82259 Grisnilimab setaritox

WT1-RTA
Grisnilimab setaritox (WT1-RTA) 是抗人 T 细胞抗体 (anti-CD7) 与蓖麻毒素 A 链 (RTA) 的结合物。RTA 是一种质量为 30 kda 的肽，能迅速活化 60S 核糖体亚基。Grisnilimab setaritox 对体外 CEM (T 淋巴母细胞白血病) 细胞具有显著细胞毒性，ID50 为 53 pM，并在恒河猴白血病性脑膜炎模型中显示出疗效改善。
TP2478 WT-1 A1

Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu
WT-1 A1 is an attractive target for immunotherapy in patients with pancreatic adenocarcinoma.
T81328 Quazomotide

Quazomotide为WT1 II类肽表位，具有RSDELVRHHNMHQRNMTKL序列。该化合物通过特异性激活CD4(+)反应，以识别并攻击WT1(+)肿瘤细胞。同时，Quazomotide作为一种主动免疫治疗剂，用于抗肿瘤疗法。

化合物

Grisnilimab
Cat.No: T82260
Synonym: WT1
Target:
Grisnilimab setaritox
Cat.No: T82259
Synonym: WT1-RTA
Target:
WT-1 A1
Cat.No: TP2478
Synonym: Tyr-Met-Phe-Pro-agn-Ala-Pro-Tyr-Leu
Target:
Quazomotide
Cat.No: T81328
Synonym:
Target:
Species：
Human (6)
Human & Mouse (2)
Expression System：
HEK293 Cells (6)
E. coli (2)
Tag：
C-His-Avi (5)
C-His (1)
N-6xHis-SUMO (1)
N-GST (1)
Cat. No. Product Name Species Expression System
TMPK-01554 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi)

WT1,WT33,WIT-2,NPHS4GUD,AWT

Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01523 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

WAGR,WT33,AWT1,GUD,RMF,WT

Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01548 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,WIT-2,AWT1,GUD,WAGR,WT1

Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01549 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi)

RMF,WAGR,MHC,GUD,NPHS4GUD,WT1,WT3...

 Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPK-01522 Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,...

 Human & Mouse HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.
TMPH-02312 Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may b...
TMPY-00140 ABP1/AOC1 Protein, Human, Recombinant (His)

amine oxidase, copper containing 1,DAO,ABP1

Human HEK293 Cells
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co...
TMPY-02402 WTAP Protein, Human, Recombinant (GST)

Mum2,Wilms tumor 1 associated protein

 Human E. coli
Wilms' tumor 1-associating protein (WTAP) was previously identified as a protein associated with Wilms' tumor-1 (WT-1) protein that is essential for the development of the genitourinary system. WT1 was originally identified as a tumor suppressor for Wilms' tumor, but it is also overexpressed in a variety of cancer cells. The WTAP-WT1 axis in vascular cells suggest that WTAP is a vital and multifaceted regulator of vascular remodeling. WTAP has been suggested to function in alternative splicing, ...

重组蛋白

HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01554
Species: Human
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01523
Species: Human & Mouse
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01548
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01549
Species: Human
Expression System: HEK293 Cells
Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)
Cat.No: TMPK-01522
Species: Human & Mouse
Expression System: HEK293 Cells
Wilms tumor protein/WT1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02312
Species: Human
Expression System: E. coli
ABP1/AOC1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00140
Species: Human
Expression System: HEK293 Cells
WTAP Protein, Human, Recombinant (GST)
Cat.No: TMPY-02402
Species: Human
Expression System: E. coli
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