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Cat. No. | Product Name | Target | Signaling Pathways |
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T81345 |
Puxitatug
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Puxitatug是一种针对[Homo sapiens VTCN1 (包含T细胞激活抑制剂1、B7家族成员H4、B7H4、B7-H4的Vset结构域)]的Homo sapiens免疫球蛋白G1-κ型单克隆抗体。 |
Cat. No. | Product Name | Species | Expression System |
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TMPK-00172 |
B7-H4 Protein, Human, Recombinant (His & Avi)
B7H4,B7x,VTCN1,PRO1291,B... |
Human | HEK293 Cells |
B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status . | |||
TMPJ-00175 |
B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
V-set domain containing T cell activation inhibitor 1 |
Rhesus | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the s... | |||
TMPJ-00176 |
B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
B7H4T-cell costimulatory molecule B7x,FLJ22418,B7XP... |
Human | HEK293 Cells |
B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine ... |