Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35081 |
VU0486321
VU 0486321,VU-0486321 |
Others | Others |
VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/min/kg,t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02). |