Cat. No. | Product Name | Target | Signaling Pathways |
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T17240 | VU041 | Others | Others |
VU041 is an inhibitor of Anopheles gambiae and Aedes aegypti inward rectifier potassium 1 channels (IC50: 2.5 μM and 1.7 μM, respectively). VU041 inhibits appreciably is mammalian Kir2.1 (IC50: 12.7 μM) and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. | |||
T29133 |
VU0410150
VU-0410150,VU 0410150 |
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VU0410150, a pyrrylarylsulfone containing compound, has been found to be a mGluR4-positive allosteric modulator and has been evaluated as a potential drug for the treatment of Parkinson’s disease. | |||
T24945 |
VU0410425
VU 0410425,VU-0410425 |
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VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator. | |||
T24946 |
VU0415374
VU 0415374,VU-0415374 |
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VU0415374 is a positive allosteric modulator of mGlu4. | |||
T29134 |
VU0418506
VU-0418506,VU 0418506 |
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VU0418506 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGlu4). |