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Cat. No. | Product Name | Target | Signaling Pathways |
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T40475 |
Ceftobiprole medocaril
BAL5788,头孢比普酯 |
Antibacterial | Microbiology/Virology |
Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素,对耐甲氧西林金黄色葡萄球菌具有活性。 | |||
TQ0077 |
Ceftobiprole
Ro 63-9141,BAL 9141,头孢吡普 |
Antibacterial | Microbiology/Virology |
Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素,对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。 | |||
T61121 | NusB-IN-1 | ||
NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1]. | |||
T61799 | Antibacterial agent 75 | ||
Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in reference [1]. | |||
T72141 |
Ceftobiprole medocaril sodium
头孢比普酯钠盐,BAL5788 sodium |
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Ceftobiprole medocaril (BAL5788) sodium 是 Ceftobiprole 的胃肠外前药。Ceftobiprole 是一种非肠道吡咯烷酮头孢菌素。Ceftobiprole 是一种广谱头孢菌素,对甲氧西林 (MRSA) 和耐万古霉素葡萄球菌 (VRSA) 和耐青霉素链球菌具有高水平的体外活性。Ceftobiprole 也抑制革兰氏阳性和革兰氏阴性病原体。 | |||
T37263 |
14-methyl Pentadecanoic Acid methyl ester
|
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14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluvialis microalgae. It is a major component of the vancomycin-induced biofilm produced by vancomycin-resistant S. aureus (VRSA). 14-methyl Pentadecanoic acid methyl ester has been used as a standard for the quantification of 14-methyl pentadecanoic acid in various foods by GC-MS. | |||
T14359 |
AVX 13616
|
Others | Others |
AVX 13616 shows the potent in vivo antibacterial activity of Avexa’s lead antibacterial candidate; particularly against drug-resistant Staphylococcus pathogens. IC50 value: 2-4 ug/ml (MICs) Target: antibacterial agent AVX13616 was as active as mupirocin i |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75278 | Pristinamycin | ||
Pristinamycin, 一种 Streptomyces pristinaespiralis 产生的口服活性链霉素样抗生素,由化学上不相关的两部分组成:Pristinamycin I (PI) 与 Pristinamycin II (PII)。该药物对包括耐甲氧西林金黄色葡萄球菌 (MRSA)、万古霉素耐药金黄色葡萄球菌 (VRSA) 和粪肠球菌 (VREF) 在内的多种抗生素耐药革兰氏阳性菌表现出强大活性。 |