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抑制剂 & 化合物

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重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T36296	BIO5192 hydrate
	BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2]. The combination of BIO5192 hydrate (1 mg/kg; i.v.) and Plerixafor (5 mg/kg; s.c.) exert an additive effect on progenitor mobilization[1].BIO5192 hydrate (30 mg/kg; s.c; bid; during days...

化合物

BIO5192 hydrate

Cat.No: T36296

Species：

Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPY-00476	ITGB1 Protein, Human, Recombinant (His) VLAB,integrin, beta 1 (fibronectin recepto...	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe...
TMPJ-00786	ITGB1 Protein, Human, Recombinant (aa 21-728, His) Integrin Beta-1,VLA-4 Subunit β,Fibronecti...	Human	HEK293 Cells
	Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree...

重组蛋白

ITGB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00476

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (aa 21-728, His)

Cat.No: TMPJ-00786

Species: Human

Expression System: HEK293 Cells

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