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Cat. No.	Product Name	Target	Signaling Pathways
T37447	UZH1 UZH1
	UZH1 is a racemate of UZH1a and UZH1b. UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1b (IC50=28 μM) is essentially inactive. UZH1 can be used for epitranscriptomic modulation of cellular processes. UZH1 has antitumor activity. UZH1 also can be used as a chemical probe for studying METTL3[1]. UZH1a (2.5-160 μM; 72 h) inhibits the growth of MOLM-13, HEK293T, and U2Os cells, with IC50s of 11 μM, 67 μM, and 87 μM, respectively[1].UZH1b (2.5-160 μM; 72 h) inhibits the ...
T37448	UZH1a
	UZH1a is a potent and selective inhibitor of METTL3, exhibiting an IC50 of 280 nM. It serves as a tool for epitranscriptomic modulation of cellular processes and possesses antitumor activity. Additionally, UZH1a functions as a chemical probe for the study of METTL3[1].
T78133	UZH1b	Others	Others
	UZH1b为UZH1a（METTL3抑制剂）的对映异构体，其对METTL3具有极低活性（IC50=28 µM）。