Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02426 |
UBE2D1 Protein, Human, Recombinant (His)
UBC4/5,E2(17)KB1,ubiquitin-conjugating enzyme E2D 1,UBCH... |
Human | E. coli |
Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant... | |||
TMPJ-00999 |
UBE2D1 Protein, Human, Recombinant (GST)
Ubiquitin-conjugating enzyme E2(17)KB 1,UB,UbcH5,UB... |
Human | E. coli |
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transc... |