Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01322 |
TWSG1 Protein, Human, Recombinant (His)
TSG,Twisted Gastrulation Protein Homolog 1,TWSG... |
Human | HEK293 Cells |
Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to B... | |||
TMPY-02807 |
TWSG1 Protein, Mouse, Recombinant (His)
Twg,Twsg1,9030422N06Rik,AW552143,... |
Mouse | HEK293 Cells |
TWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone ... |