Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01298 |
CADM1 Protein, Human, Recombinant (His)
Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSL... |
Human | HEK293 Cells |
CADM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9BY67-1. | |||
TMPK-00495 |
CADM3 Protein, Cynomolgus, Recombinant (His)
NECL1,IGSF4B,CADM3,TSLC1-like |
Cynomolgus | HEK293 Cells |
Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compa... | |||
TMPY-04499 |
CADM1 Protein, Mouse, Recombinant (His)
Igsf4a,Necl2,RA175N,cell adhesion molecule 1 |
Mouse | HEK293 Cells |
CADM1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q8R5M8-2. | |||
TMPJ-00281 |
CADM1 Protein, Mouse, Recombinant (hFc)
IgSF4,NECL-2,Nectin-like protein 2,Immunoglobulin superfamil... |
Mouse | HEK293 Cells |
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in... |