Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70765 |
TRV0109101
|
Others | Others |
TRV0109101 is a G protein-biased agonist of the µ-opioid receptor. | |||
T70763 |
KR-67607
|
Others | Others |
KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat eyes. KR-67607 showed its protective effects against ischemia-reperfusion-induced eye injury. KR-67607 effectively reduced cortisol levels in mouse eyes and maintained the trabecular meshwork (TM) structure in the presence of transient ischemic stress. Furthermore, KR-67607 rever... |