2
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17110 |
TNP-470
AGM-1470 |
Others | Others |
TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor. | |||
T68406 |
A-849519
|
||
A-849519 is a reversible inhibitor of MetAP2 that has demonstrated anti-angiogenesis and anticancer activity in a number of in vitro and in vivo models. In this study, we evaluated the anticancer activity of A-849519 in a modified Dunning model of androgen-independent prostate cancer and compared its efficacy with TNP-470, an established MetAP2 inhibitor. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6745 |
PALATINOSE
TNP-470,帕拉金糖水合物,Isomaltulose |
Others | Others |
PALATINOSE (TNP-470) 是一种天然存在的二糖,由α-1,6-连接的葡萄糖和果糖组成。PALATINOSE 对肝脏代谢功能具有有益的影响,因此可能是蔗糖甜味剂的良好替代品。 | |||
T9155 |
Fumagillol
|
Others; Antibacterial | Microbiology/Virology; Others |
Fumagillol 是有效的血管生成抑制剂 TNP-470 和 fumagillin 的直接前体。Fumagillin 作为一种抗菌药物,是选择性有效血管生成抑制剂。 |