Cat. No. | Product Name | Target | Signaling Pathways |
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T40321 |
TNF-α-IN-6
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TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM). | |||
T69223 |
CC-1088
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CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6). | |||
T81838 |
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human)
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Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) 为一种基于FRET (荧光共振能量转移) 原理的多肽底物,通过其裂解引起的荧光强度变化来评估其活性。 | |||
T78434 |
Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA
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Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) TFA 为基于荧光共振能量转移的多肽底物,通过裂解引起的荧光强度变化来确定其活性。 |