Cat. No. | Product Name | Target | Signaling Pathways |
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T40040 |
TLR8 agonist 2 hydrochloride
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TLR8 agonist 2 hydrochloride is a highly potent and selective agonist for human TLR8, exhibiting an EC50 of 3 nM. However, its activity towards human TLR7 is considerably weaker, with an EC50 of 33.33 μM. | |||
T60517 | CL097 hydrochloride | ||
CL097 hydrochloride 是一种有效的 TLR7和 TLR8激动剂。CL097 hydrochloride 可在巨噬细胞中诱导促炎细胞因子和 NADPH 氧化酶启动活性,从而增加 fMLF 刺激的ROS 产生。 |