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Cat. No. Product Name Target Signaling Pathways
T79069 TLR7/8 agonist 9

TLR7/8 agonist 9 (Compound 25a) 是一种能够增强PD-1/PD-L1阻断疗法抗肿瘤效果的化合物,主要用于癌症免疫疗法研究。它对hTLR7和hTLR8的EC50分别为40 nM和23 nM,显示出其对这两种受体的高亲和力以及潜在的抗肿瘤活性。
T39970 TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7/8 agonist 4, a potent TLR7/8 agonist, linked to the ADC linker hydroxy-PEG10-acid which can be cleaved.
T39968 TLR7/8 agonist 4 hydroxy-PEG10-acid

TLR7/8 agonist 4 hydroxy-PEG10-acid

TLR7/8 agonist 4 hydroxy-PEG10-acid (compound 9) is a drug-linker conjugate employed in antibody-drug conjugates (ADC). This compound exhibits remarkable antitumor activity by utilizing TLR7/8 agonist 4, which acts as a potent activator of TLR7/8. The TLR7/8 agonist 4 is linked to hydroxy-PEG10-acid, the ADC linker, via a cleavable bond. Overall, it demonstrates promising pharmaceutical potential in the context of ADC-based therapeutics.

化合物

TLR7/8 agonist 9
Cat.No: T79069
Synonym:
Target:
TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Cat.No: T39970
Synonym: TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride
Target:
TLR7/8 agonist 4 hydroxy-PEG10-acid
Cat.No: T39968
Synonym: TLR7/8 agonist 4 hydroxy-PEG10-acid
Target:
TargetMol Loading
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